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产品目录

重组人三磷酸肌苷焦磷酸酶(ITPA)(ITPase)图片
产品货号:
JN1747
中文名称:
重组人三磷酸肌苷焦磷酸酶(ITPA)(ITPase)
英文名称:
Recombinant Human Inosine Triphosphate Pyrophosphatase
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Ala2-Ala194在C端含有His标签。

ITPase质量控制:>95%(还原性SDS-PAGE)

ITPase制剂:液体

ITPase保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于ITPase
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Defects in ITPase is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.
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